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Guidance for Control of Carbapenem-Resistant Enterobacteriaceae


This toolkit was developed by the Centers for Disease Control and Prevention (CDC) to help health care facilities protect patients from carbapenem-resistant Enterobacteriaceae (CRE) and to prevent transmission of CRE. Expanding on 2009 CDC recommendations, the toolkit offers prevention strategies for acute and long-term care facilities, as well as regional prevention strategies for health departments. It includes measures based on history of identified CRE (none, rare, or common).

The toolkit includes the following sections:
  • Introduction
  • Background
  • Definitions
  • Part 1: Facility-level CRE prevention
  • Part 2: Regional CRE prevention: recommended strategies for health department implementation

Links to the Tool:
This tool is available at:


Centers for Disease Control and Prevention

Funding Sources

Centers for Disease Control and Prevention

QualityTool Topic



  • Review Date: 03/2013
  • Original Summary: 07/2014
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Last updated: August 13, 2014.