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Guide To Developing and Managing Overdose Prevention and Take-Home Naloxone Projects


This manual is designed to outline the process of developing and managing an overdose prevention and education program, with or without a take-home naloxone component. Overdose prevention work can be easily integrated into existing services and programs that work with people who use or are affected by drugs, including shelter and supportive housing agencies, substance abuse treatment programs, parent and student groups; overdose prevention work can also be useful for groups of people who use drugs outside of a program setting.

Downloadable worksheets and resources are available via links throughout the toolkit. Additional information and resources can be found in the manual's appendix.


Harm Reduction Coalition

Funding Sources

Centers for Disease Control and Prevention; Harm Reduction Coalition

QualityTool Topic



  • Release Date: 2012
  • Original Summary: 08/2013
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Last updated: March 12, 2014.