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Guide to the Elimination of Catheter-Related Bloodstream Infections


This guide, for use by infection preventionists and quality improvement teams, provides step-by-step guidance to facilitate the bedside implementation of relevant clinical evidence and best practices for eliminating catheter-related bloodstream infections (CRBSIs). It presents simple, practical implementation strategies, tools, and resources to prevent infections, and strategies for process improvement.

Topics covered include:
  • Background
  • Purpose and objectives
  • Scope
  • Differentiating between CRBSIs and central line–associated bloodstream infections
  • Pathogenesis, epidemiology, cost, and preventability of CRBSIs
  • The evolution of CRBSI prevention efforts
  • Contemporary issues in CRBSI reduction
  • U.S. regulatory and public policy issues relating to CRBSI reduction
  • Public reporting of CRBSIs and pay-for-performance
  • Definitions used in CRBSI prevention
  • National Healthcare Safety Network surveillance definitions and methods
  • General techniques for monitoring CRBSIs
  • Case studies
  • Tools and resources
  • Web-based tools and resources
  • References


Association for Professionals in Infection Control and Epidemiology

Funding Sources

Association for Professionals in Infection Control and Epidemiology

QualityTool Topic



  • Release Date: 2009
  • Original Summary: 09/2011
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Last updated: June 13, 2012.