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Breast Cancer Treatment – Physician Data Query (PDQ®) (Health Professional Version)


This summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the treatment of breast cancer.

This summary addresses the following topics:

  • General information about breast cancer
    • Statistics
    • Patient evaluation
    • Contralateral disease
    • Hormone replacement therapy
    • Genetics
    • Follow-up
    • Breast reconstruction
  • Cellular classification of breast cancer
  • Stage information for breast cancer
  • Ductal carcinoma in situ
  • Lobular carcinoma in situ
  • Stage I, II, IIIA, and operable IIIC breast cancer
    • Primary therapy
    • Adjuvant radiation therapy
    • Adjuvant systemic therapy
    • Timing of primary and adjuvant therapy
    • Treatment options
  • Stage IIIB, inoperable IIIC, IV, recurrent, and metastatic breast cancer
    • Inoperable stage IIIB or IIIC or inflammatory breast cancer
    • Stage IV, recurrent, and metastatic breast cancer
    • Systemic therapy


National Cancer Institute

Funding Sources

National Cancer Institute; National Institutes of Health

QualityTool Topic



  • Release Date: 02/2006
  • Review Date: 02/2008
  • Recent Summary: 02/2008
  • Original Summary: 02/2006
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Last updated: November 14, 2012.